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The beta-oxidation of saturated fatty acids

Pancreatic and bile lipases hydrolyze triglycerides (lipids) to monoglycerides (fatty acids). The saturated fatty acids are transported in the mitochondrial matrix by a complex system using several enzymes (acylcoasynthetase, transferases, etc.). In the matrix they are activated by fixing $ CoASH $ and then degraded to acetylCoenzyme A which enters in the citric acid cycle (Krebs cycle).

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Steps

1 Saturated Fatty Acid 2 AcylCoA 3 EnoylCoA 4 HydroxyacylCoA 5 KetoacylCoA 6 AcylCoA 7 AcetylCoA

References

For details on the role of NAD+ look at →               this For details on the role of the FAD look at →               this For Coenzyme A - CoASH look at →               this For the Krebs cycle look at →               this